Erythema nodosum - Mezglainā Eritēma
☆ 2022. gada Stiftung Warentest rezultātos no Vācijas patērētāju apmierinātība ar ModelDerm bija tikai nedaudz zemāka nekā ar maksas telemedicīnas konsultācijām.
Tas parādās kā sāpīgs eritematozs mezgliņš uz kājas.
References
Erythema nodosum ir visizplatītākais pannikulīta veids, kam raksturīgi sāpīgi sarkani mezgliņi, kas galvenokārt atrodas uz apakšstilbiem. Tās precīzs cēlonis joprojām nav zināms, bet šķiet, ka tas ir pārspīlētas reakcijas uz dažādiem izraisītājiem rezultāts. Lai gan tā izcelsme bieži ir neskaidra, pirms primary erythema nodosum diagnosticēšanas ir svarīgi izslēgt citus pamatnosacījumus. Tas var norādīt uz sistēmisku slimību rašanos, piemēram, infekcijām, iekaisumiem, vēzi vai reakcijām uz medikamentiem. Parastie aktivizētāji ir strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis attiecas uz dažādu iekaisuma stāvokļu kopumu, kas ietekmē tauku audus zem ādas. Bērniem šie stāvokļi ir retāk sastopami. Panniculitis var būt galvenā problēma sistēmiskā stāvoklī vai sekundāra reakcija uz tādiem faktoriem kā infekcija, traumas vai noteiktas zāles. Neatkarīgi no iemesla lielākajai daļai panniculitis veidu ir līdzīgi simptomi, tostarp sāpīgi, sarkani mezgliņi zem ādas.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , zemādas tauku slāņa iekaisums, ir reta slimība, kas parasti izpaužas kā pietūkuši mezgliņi vai plankumi. Erythema nodosum (EN) ir visizplatītākais veids, ko bieži izraisa dažādi faktori. Lai gan aptuveni 55% gadījumu nav skaidra iemesla, parastie izraisītāji ir infekcijas, zāles, noteiktas slimības, piemēram, sarkoidoze un iekaisīga zarnu slimība, grūtniecība un vēzis. EN parasti parādās pusaudžiem un jauniem pieaugušajiem, biežāk sievietēm. Bieži vien pirms tās ir vispārēja slimības sajūta, kas ilgst vienu līdz trīs nedēļas, ar tādiem simptomiem kā drudzis un augšējo elpceļu problēmas. Pēc tam parādās sarkani mezgliņi, parasti roku un kāju ārējās malās, izraisot sāpes. Precīzs EN cēlonis nav pilnībā izprotams, taču tiek uzskatīts, ka tas ietver imūnkompleksus mazajos tauku slāņa asinsvados, izraisot iekaisumu. Parasti biopsija parāda iekaisumu tauku slānī, nesabojājot asinsvadus. Pat bez īpašas pamatcēloņa ārstēšanas EN bieži izzūd pati no sevis. Tātad lielākajai daļai pacientu ir nepieciešama tikai atbalstoša viņu simptomu aprūpe.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Nodosum eritēma tiek diagnosticēta klīniski. Lai apstiprinātu neskaidru diagnozi, var veikt biopsiju un mikroskopiski pārbaudīt. Lai izslēgtu plaušu slimības, jo īpaši sarkoidozi un tuberkulozi, ir jāveic krūškurvja rentgenogrāfija.